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GoodHearts Resources and Reading Room

Transplantation: An Overview

Transplantation is the act of surgically removing an organ from one person and placing it into another person. A transplant is done because the potential recipient's own organ has failed or has been damaged through illness or injury.

Since the first successful organ transplant, thousands of recipients have had their lives extended and health enhanced as a result of organ transplantation. Survival rates of recipients continue to improve, but a transplant is not a cure, it's merely a way to manage “chronic wellness”.

Transplantation also includes some negative effects on a patient's quality of life. There is the financial burden during the patient's illness, when the patient is unable to work; and the caregiver, usually a member of the family, may have to take a leave of absence or drop out of the labour force to look after the patient, take him/her to appointments, assessments prior to and after the transplant.

The cost of some medications also may play a significant role in the patient's noncompliance with treatment regimen and such disruption of the therapy eventually could lead to rejection of the transplanted organ.

There are physical side-effects as well as psychological and social issues that must be addressed after transplantation. Positive outcomes require provisions for patient education and support services that go beyond the medical needs following transplantation.

Recipients know best the real value of increasing the number of donated organs: an extended lifetime, improved quality of life and a chance to resume activities that would have been precluded without a transplant.

Families often view organ donation as a way to redeem an otherwise tragic situation; as a way to honour their loved one's life, passion and philosophy; and as a way to help others live.

Cultural and religious traditions and beliefs about the treatment of the dead body, beliefs about life after death and fears of mutilation can influence decisions about organ donation.

Several studies have addressed the economic value of increased organ donation. They estimate that, on average, a deceased organ donor adds 13 quality-adjusted life years to a recipient. Assuming a life year is worth $100,000, then each donor is worth $1,085,000 to society.

Transplants are cost-effective. For patients with kidney disease, for instance, the average cost of dialysis treatment is $50,000 a year. The one time cost of a kidney transplant is approximately $20,000 and the annual costs of anti-rejection medications is about $7,000.

Canada's donor rate is among the lowest in the industrialized world Ñ about 14-15 people per million. GoodHearts encourages Canadians to register their wishes to donate, if a registry is available in their province, and discuss their decision with their family members.

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Transplantation in the Capital Health Region (Edmonton, AB)

The first organ transplanted at the University of Alberta (U of A) Hospital was a kidney in 1967. Since that historic kidney transplant, close to 4,000 solid organs and countless tissue have been transplanted at the largest transplant centre in Western Canada.

Solid organ transplants performed at the U of A Hospital include heart, lung, liver, kidney and intestines. The world-renown Islet Transplant Centre is located here as is Canada's first Comprehensive Tissue Centre to be accredited by the American Association of Tissue banks.

Dr. Dennis Modry performed the first heart transplant in Western Canada in 1985. Since that historic moment, more than 500 people have received this wonderful gift of a renewed life at the U of A Hospital.

Found at the U of A Hospital site, the Stollery Children's Hospital is equally successful and progressive with its pediatric heart transplant program and the Mazankowski Alberta Heart Institute opened in 2008.

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Transplantation on the Web

Capital Health Region (Edmonton, AB): www.capitalhealth.ca

Organ & Tissue Donation : F.A.Q.
Tissue Transplantation
Heart Transplantation
Lung Transplantation
Pancreas Transplantation
Kidney Transplantation
Liver Transplantation

Canadian Institute for Health Information
Canadian Organ Replacement Register: CORR e-statistics on transplantation

Medline Plus: Organ Transplantation

MedHunters.com: Transplant Timeline

British Columbia Transplant Society: www.transplant.bc.ca

London (ON) Health Sciences Centre: Multi-Organ Transplant Program

Toronto General Hospital: Multi-Organ Transplant Program

Wikipedia: Organ Transplants

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Your Stories

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Speakers Bureau
Please contact us if you would like a transplant recipient to speak to your group.